E-Articles - Health and Fitness

Statistics indicate that eight out of ten people suffer from acne in their teenage years. No research has to be do

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ne to prove that but everyone does get to experience acne breakouts once in their lifetime. For some people it qui

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

kly passes on as they age and their body, lifestyle, environment and skin regimen changes. For others, acne proble

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s become a lot worse and may unfortunately leave not just physical scars, but emotional trauma.

Sebaceous glands

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ound in the follicles of our skin contain fatty tissues that help lubricate our hair and epidermis. These fatty oi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s keep our skin in a healthy condition. Acne forms as a result of the fatty oils, also known as sebum, being block

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d by our skin’s dead cells. They form into pimples, whiteheads or acne and worsen as it gets infected.

Most commo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ly affected by acne breakouts are teenagers who are still developing into puberty. However, adult acne is also ver

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

common among those people between twenty and forty years old. Some of the factors that cause acne breakouts among

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the adult population include lifestyle, stress and toxins from the environment, make-up, use of medicine and other

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

anti-biotic, emotional problems and hormonal changes in the body.

Adult women are very prone to acne because some

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

tend to use the wrong kind of beauty products for their skin. They also undergo serious hormonal changes as they

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

each the age of menopause. However, adult acne is not just limited to women, as men do get the same problem. Part

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

f this has to do with hygiene and taking care of one’s body. Smoking or drinking too much; not eating the right ki

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d of food; or working too hard and not getting enough sleep are some of the things that might not only cause one’s

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

health to deteriorate, and it can also contribute to acne.

In treating acne conditions, a big lifestyle change ma

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

be in order for some people. The right kind of food to eat; the right amount of sleep; the way one handles stress

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

the environment one moves around in have to be altered or modified. Acne is also treatable with vitamins and caps

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

les containing Vitamin A, B1 or E. This should help boost the body’s immune system from infection. In really extre

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e cases, acne may also be treated with prescription drugs which should be recommended by a very good dermatologist

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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