Tags |
|
|
Links |
|
|
E-Articles - Dash Diet: The No-Pain Diet
A group of researchers from 5 major medical centers found
that eating a specific diet rich in nutrient-dense fruits
and vegetables, whole grains and low fat dairy can be a
powerful tool in lowering blood pressure.
The DASH DIET( Dietary Appr
The DASH DIET( Dietary Appr
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
oaches to Stop Hypertension) was
found in 1996 to lower blood pressure about the same as a
blood pressure medication would, and since that time has
quickly become one of the most often prescribed diets in
clinical practice today.
The DASH D
The DASH D
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
et is recommended by the American Heart
Association, in the USDA's 2005 Dietary Guidelines for
Americans, and is featured in the US High Blood Pressure
Guidelines.
The DASH DIET Study 459 people were chosen to participate in the DASH DIET St
The DASH DIET Study 459 people were chosen to participate in the DASH DIET St
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
dy. They were randomly assigned to one of three different types:
·The "typical American diet"
·A diet with more fruits and vegetables, but otherwise similar to the typical American diet
·The "DASH diet" - rich in fruits, vegetables, and low-
·The "typical American diet"
·A diet with more fruits and vegetables, but otherwise similar to the typical American diet
·The "DASH diet" - rich in fruits, vegetables, and low-
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
at
dairy products; moderate in fish, poultry, and nuts; and
reduced in red meat, sweets, and sugar-sweetened drinks.
To assure they weren't doing anything else that might lower their blood pressure, participants were asked not to make any m
To assure they weren't doing anything else that might lower their blood pressure, participants were asked not to make any m
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
jor changes in the physical activity levels during the
study.
Participants were weighed frequently to make sure their weight stayed constant; if someone gained or lost weight, they were given a bit less or more food to eat to get their weig
Participants were weighed frequently to make sure their weight stayed constant; if someone gained or lost weight, they were given a bit less or more food to eat to get their weig
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
t back to what it was.
Salt/sodium intake was the same in all three diets - slightly lower than the U.S. average, but still higher than what most guidelines recommended.
The Results
Those who ate the typical American diet did not see a cha
Salt/sodium intake was the same in all three diets - slightly lower than the U.S. average, but still higher than what most guidelines recommended.
The Results
Those who ate the typical American diet did not see a cha
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
nge in their blood pressure.
Those on the fruit and vegetable diet experienced a significant lowering of their systolic blood pressure - The upper number, which is a measurement of blood pressure in the arteries when the heart contracts to p
Those on the fruit and vegetable diet experienced a significant lowering of their systolic blood pressure - The upper number, which is a measurement of blood pressure in the arteries when the heart contracts to p
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
mp out blood -
but little change in their diastolic pressure.
But the men and women who ate the DASH DIET for eight weeks experienced a significant drop in both their systolic and diastolic blood pressure readings. Changes occurred within a
But the men and women who ate the DASH DIET for eight weeks experienced a significant drop in both their systolic and diastolic blood pressure readings. Changes occurred within a
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
eek of starting the DASH diet, stabilized within two weeks,
and stayed lowered for the remainder of the eight weeks.
On average, blood pressure fell 5.5 mmHg (systolic) and 3.0 mmHg (diastolic) among all participants (including both those wi
On average, blood pressure fell 5.5 mmHg (systolic) and 3.0 mmHg (diastolic) among all participants (including both those wi
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
h normal blood pressure and those with
hypertension).
In participants with high blood pressure, blood pressure dropped an average of 11.4 mmHg (systolic) and 5.5 mmHg (diastolic).
These improvements in blood pressure are about the same as
In participants with high blood pressure, blood pressure dropped an average of 11.4 mmHg (systolic) and 5.5 mmHg (diastolic).
These improvements in blood pressure are about the same as
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
hat can be achieved with a single antihypertensive
medication.
There were positive health outcomes of the DASH diet beyond lowering high blood pressure.
Most importantly, perhaps, the DASH diet lowered the study participants'cholesterol lev
There were positive health outcomes of the DASH diet beyond lowering high blood pressure.
Most importantly, perhaps, the DASH diet lowered the study participants'cholesterol lev
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ls.
When blood cholesterol is high, cholesterol and other fatty substances collect on the walls of your blood vessels and in time restrict or block the flow of blood to your heart.
High cholesterol, which is generally caused by a diet high
When blood cholesterol is high, cholesterol and other fatty substances collect on the walls of your blood vessels and in time restrict or block the flow of blood to your heart.
High cholesterol, which is generally caused by a diet high
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
n saturated fats, is a major risk factor for heart disease.
The DASH diet is low in total and saturated fat.
People who ate the diet during the study, dropped their cholesterol 14 points. The "bad" cholesterol (LDL) fell 11 points. The level
The DASH diet is low in total and saturated fat.
People who ate the diet during the study, dropped their cholesterol 14 points. The "bad" cholesterol (LDL) fell 11 points. The level
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
of good cholesterol (HDL) also fell by 3.7
points (this type of drop in HDL is seen when people reduce
their overall fat intake). Combining all the effects
(changes in blood pressure, LDL, and HDL), there was an
important improvement in ove
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
all cardiac risk with the DASH
DIET.
A later study was done at the Boston University Medical Center, which offered the DASH Diet in an online form to employees of a large US company.
Over 4,000 people enrolled in the DASH DIET program.
The
A later study was done at the Boston University Medical Center, which offered the DASH Diet in an online form to employees of a large US company.
Over 4,000 people enrolled in the DASH DIET program.
The
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
received weekly email reminders to log in to the site
for information on topics such as weight loss, exercise,
reading food labels, grocery shopping and more.
They also were encouraged to track the changes they made to their diet, exercise,
They also were encouraged to track the changes they made to their diet, exercise,
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
eight and blood pressure online.
After one year in the DASH DIET program, study participants had lost weight and lowered their blood pressure significantly.
They started eating more fruits and vegetables and moved from higher fat dairy prod
After one year in the DASH DIET program, study participants had lost weight and lowered their blood pressure significantly.
They started eating more fruits and vegetables and moved from higher fat dairy prod
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
cts to lower fat versions.
After the success of the DASH DIET program, the researchers decided to offer the program to the general population online at DASH DIET
The reason the researchers think that the DASH DIET is perfect for all America
After the success of the DASH DIET program, the researchers decided to offer the program to the general population online at DASH DIET
The reason the researchers think that the DASH DIET is perfect for all America
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
s is that it doesn't take a whole
lot of learning.
It deals with real foods that are easily found in every grocery store across America, and allows dieters to choose how they plan to meet their food servings goals with foods that they enjoy
It deals with real foods that are easily found in every grocery store across America, and allows dieters to choose how they plan to meet their food servings goals with foods that they enjoy
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/275819/e-article-Dash-Diet-The-NoPain-Diet.html">Dash Diet: The No-Pain Diet</a>
BB link (for phorums):
[url=http://www.e-article.org.ua/article/275819/e-article-Dash-Diet-The-NoPain-Diet.html]Dash Diet: The No-Pain Diet[/url]
Related Articles:
Bookmark it:
|