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Biology is entering into a paradigm shift finally giving up the theory that we are all controlled by our genes.

Current science beliefs that we are not as powerful as our genes. The problem with this belief system is

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

it extends to such a degree that it makes us irresponsible. If happiness is determined by our genes than the moment we am born our happiness unfolds according to the program of the genes. There is nothing we can do a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

out it.

Bruce Lipton's ground-breaking scientific experiments prove our genes are not the brain of our cells as our biology books continues teaching today. Experimenting with cells he took out the nucleus, only to di

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

scover the cells continue to live for weeks longer. His conclusion is obvious – the nucleus with its DNA is not the brain of the cell, and therefore does not control the cell.

The nucleus of the cell contains 50% DNA

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

and 50% protein. Scientists have analyzed the cell and in doing so, looked only at the DNA discarding the proteins. The DNA is the reproductive system for the proteins. If a protein is not available, but is needed for

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

an environmental response, it can be built from the blueprint that the DNA provides.

So what is controlling the cell? Astonishing as it sounds it is the environment and its perception of it!

The perception of the c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ll is experienced through the skin. The skin contains hundreds of proteins that act as preceptors and effectors. Preceptors are triggered by environmental signals like temperature and light. This primary signal is the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n translated inside the cell becoming a secondary signal, activating the protein to do something, for example, to break apart an enzyme.

We are all made up of trillions of cells. Our bodies and organs share the same

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

attern. There is one big difference, and that is our ability to perceive an environmental signal. Perception is influenced by our beliefs. I can experience a healthy environment and at the same time believe it is not

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

healthy for me. By believing this I am changing my perception, and therefore changing my cellular behavior. For example a specific protein that is necessary in building my immune system cannot be reproduced. That lead

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

to a reduced immune system and might be the beginning of a dis-ease.

Cells have two basic behaviors: growth and protection. The cell can chose only one at a time, either it is in growth mode or in protection mode. O

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

her behaviors are more neutral but not applicable for understanding our current scenario.o

Our system cannot grow if we are in protection mode. Protection mode is another form of stress. If our system is in constant

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

stress mode then there is no possibility to growth. However growth is an essential part of our evolutionary survival strategy and if we are not growing we are stagnating and creating the chance for dis-ease.

What doe

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

this all mean? It is a faulty assumption that we are controlled by our genes. There are no cancer genes. It is not possible for a gene to activate or change on its own, for example, producing cancer. It is the enviro

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nmental signal and our perception (belief) that contributes to a change in our system.

Conclusion:

Bruce Lipton's teaching on cellular biology takes listeners into the microscopic world, where new discoveries and re

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

earch are revolutionizing the way we understand life, evolution, and consciousness. Dr. Lipton shares his lucid and startling insights about the building blocks of life, and how each of our cells has far greater innat

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e intelligence than we once believed.

Thinking we are controlled by our genes can directly be linked to the world around us, more importantly, to our perception of our environment. Perception is highly influenced by

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ur beliefs, therefore beliefs control our genes!

The bottom line is this, we are all powerful. We have power over the unfoldment of our life. We have power over which genes can be activated. We are not a the victims

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

of our genes. What we have to do is select the appropriate beliefs according to our environment.

If you wake up in the morning with a sore throat it does not mean you are getting a cold. This is actually a belief you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

either made up on your own, or took on from someone else (maybe your parents).

There is no reason to live your entire life holding onto a certain belief. We can change our beliefs like we change a CD in our CD player

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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