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    Mental preparation is something we do not often take into consideration when embarking on dietary changes. We prepare mentally for exams, activities, job interviews, but
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    who ever thinks we need to mentally prepare to change our diets? Any change we make to our current life-style and dietary habits require some form of mental preparation t
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    achieve the desired results.

    You have to know what motivates you and what motivates change. You will experience days where you will feel like defeating your hard work.
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    Will power and social influences are the most common defeaters. But with careful planning and future pacing you will identify hidden obstacles and move forward with littl
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    disruption to your goals.

    So you have decided you want to DETOX. You have read numerous articles and heard the DETOX buzzword mentioned around the hip and trendy. You m
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ay know the physical reasons for wanting to DETOX; weight loss, food intolerance, bloating or just to get into great shape for summer or that special occasion.

    Whatever
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    our reasons for DETOXING may be, you need to take into consideration the WHY behind the WHY. Knowing why will identify you deep level motivation and passion for achieving
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    your goal. WHY holds value and is of great importance to your sub-conscience, this reason alone will be enough to motivate you and will be the deciding factor on whether
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    you complete or DETOX successfully or not.

    Think back in the past, what triggered you to change your diet. Was this trigger physical or emotional? What words and picture
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    s were associated to this trigger? How did you feel? What words did you say to yourself? These questions uncover the underlying reason why you decided to take action in t
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e past.

    Before discovering your motivation for DETOXING, think about what results you achieved in the past. Answer the following questions truthfully.

    What have you hav
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    e tried in the past?
    What results did you achieve?
    What prevented you from achieving your goal at the time?
    What would you do differently this time arou
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    d?
    Next, think about what is going on in your life right now that you would like to change. What are you so tired of living with?

    By successfully identifiying wha
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    t motivated you in the past, the results you achieved then you can specifically identify what you would like to change today.

    Reaching for success: WHY

    Why do you want
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    o detox? Make sure you state your goals in positive terms and be specific. E.g. I WANT to feel energized. Instead of I DON'T want...

    Once you have stated all your goals
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    in positive terms, consider these questions and relate them to each goal.

    How will look once you have achieved your goal?
    What kind of things are you saying to you
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    self?
    What are people saying about you?
    What are you doing? E.G. shopping for new clothes, taking part in a new activity.
    How are you feeling at this ti
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    me?
    On a scale of 1-10 (1-low 10 -high) how motivated are you to begin your DETOX?
    What could prevent you from completing your DETOX
    What could you do to
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    top these obstacles from stopping you?

    A well thought out plan accompanied by support, motivation and understanding as to why you are embarking on a specific goal provid
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    es the necessary groundwork or foundation for success. Apply this strategy not just to your health but your life and starting living your dream of a healthy body and mind


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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