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  • E-Articles - Dreams and Creativity

    Dreams do tell us who we are and what interests us. Dreams help creative persons to create their best. Goethe solved many definite scientific probl
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ems in his dreams and also composed poems.

    La Fontaine composed ‘The Fable of Pleasures’ in his dream. Coleridge was in deep sleep, when 200 to 30
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    0 lines of the, ‘Rime of the Ancient Mariner’ came to him and he was fortunate enough to wake instantly and write them. The same process occurred wi
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    th Kubla Khan’. Bernhard Palissay made one of his most beautiful ceramic pieces on dream inspiration.

    Maury confesses: “I have had in dream ideas
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    and inspiration that could never have entered my consciousness when I awake.” R L Stevenson’s ingenious plots were evolved in his dream state. The
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    chapter on ‘Dreams’ by him in his volume ‘Across the Plains’ contains a description of most successful dream experiments thus far recorded. Yeats,
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    Tennyson, Walter de la Mare, Richard Church are the poets to whom inspiration came in dreams.

    Materlink also frequently dreamed parts of his books
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    and wrote, “Unless we are guilty of Systematic and childish incredulity, we are compelled to admit that prophetic dreams have always existed and t
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    hey must definitely be classed among the most defensible acquisitions of metaphysics.” Srinivasa Ramanujan, the great mathematical genius of Tamiln
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ad, India worked out mathematics during dreams.

    Mr. Subbarayan wrote:”Ramanujan was staying for sometime with my father in Triplicane, Madras. Both
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    of them used to work mathematics on slates till 11.30 pm.

    On several days during this period Ramanujan would get up from sleep at about 2 p.m and
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    write down something in the slate in the dull light of the hurricane lamp. In regard to this action, he used to say that he worked out mathematics i
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    n his dreams and was jotting down the results then and there to remember them the next day.

    The celebrated mathematician, Henri Poincare, tried day
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    after day to discover some general method by which a whole group of equations could be solved. He related that one night he retired to rest, after
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    thinking deeply on the problem for a long time, and on getting up the next morning discovered to his intense surprise on his table several sheets of
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    paper on which he had worked out a complete solution to the problem.

    In 1932, the famous naturalist Professor Agassiz was busy with his monumental
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    study of fossil fishes. In one case he could not reconstruct the fish from the imprint left on the slab. At this juncture he experienced three drea
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ms of the fish on succeeding nights. In the third dream the entire fish stood reconstructed before him. He then drew on paper in the dark a copy of
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    his vision and on consulting the slab in the morning found that the dream reconstruction was correct.

    There are hundreds of such incidents one may
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    quote. One after other the great writers, poets and artists confirm the fact that the work comes to them from beyond the threshold of consciousness


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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