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Each of us has numerous opportunities to make a difference in the lives of others or the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

world in general. Each day people cross our path: strangers, clients, friends and relati

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

es that give us the opportunity to touch them in a positive way. We can offer them:

-a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ind word.
-a special favor
- positive acknowledgment
-a simple smile

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

a listening ear
-an open mind
-a receptive heart
-encouragement
-beli

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ef in them and their ideas, goals and dreams
-tough love

There is more but I am sur

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

I have made my point. We don’t have to be best-selling authors, world renown speakers,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

owerful leaders or special people of any kind. Each of us in our own way has something v

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ry special to give to the world and its positive future.

You may never know how a kind w

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ord from you at just the right moment or a little encouragement in times of discouragemen

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

that someone may face can have a tremendous long-term impact on the rest of their life.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

There are so many ways you can touch people, sharing your gifts of energy, ideas, time, c

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

unsel, love, support and belief that will help them along their journey. And, the intere

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

sting thing is that once you touch just one person they may go out and touch one also. B

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fore you know it your simple act or words may have touched thousands of lives for the bet

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

er.

-How are you making a difference in the world today?
-What legacy will you le

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ve behind as evidence that you once traveled planet Earth?
-Who have you helped

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

recently?
-Who has helped you in some way?
-Did you share your gratitude with t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

em?
-Did you pass along the kindness in some other way to the next person who cro

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

sed your path?

I challenge you to make a positive difference - today - in someone’s life

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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An article at CNN lists academic research scientists as one of the top three “Big jobs that pay badly”. The article states that this career track has “one of the most disproportionate ratios of training to pay”.

An often misunderstood reality of Pay Per Click Advertising is that often times you can't determine which sites your ads will appear on. How does this impact your Pay Per Click Advertsing strategy?

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